Kono Chem Co.,Ltd

Glutathione, Astaxanthin, Resveratrol, Quercetin, Rutin and other APIs

Product Certification

Kono Chem Co.,Ltd

Country:China (Mainland)

Business Type:Other

Assessed supplierAssessed
supplier

qq

    x
  • Mr.Sam
  • Ms.Sarah
  • Mr.Edward

Contacts

  • Mr.Hong
    Tel: 86-29-86107037-8015

  • Mr.Sam
    Tel: 86-29-86107037-8016

  • Ms.Sarah
    Tel: 86-29-86107037-8019

  • Mr.Edward
    Tel: 86-29-86107037-8021

  • Ms.Freya
    Tel: +86 29 86107037-8010

  • Ms.Jessica
    Tel: 029-86107037-8014

  • Mr.Gao
    Tel: +8613289246953

  • Fax: 86-29-81330164
  • URL: http://www.konochem.com
  • Province/state: Shaanxi
  • City: Xi'an
  • Street:No.11 Daqing Road,Lianhu District,Xi’an 710082,China
E-MAIL Supplier    Clike here
Home > Products > 

CAS:154229-19-3 Abiraterone 99%

CAS:154229-19-3 Abiraterone 99% CAS NO.154229-19-3

  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,MoneyGram,Other
  • Product Details

Keywords

  • Abiraterone
  • Abiraterone high purity
  • Androsta-5,16-dien-3-ol,17-(3-pyridinyl)-, (3b)-

Quick Details

  • ProName: CAS:154229-19-3 Abiraterone 99%
  • CasNo: 154229-19-3
  • Molecular Formula: C24H31NO
  • Appearance: White powder
  • Application: Medicine
  • DeliveryTime: within 3-4days after received your pay...
  • PackAge: according to customers' requirements
  • Port: all chinese port
  • ProductionCapacity: 100 Kilogram/Week
  • Purity: 99.5%
  • Storage: store in cool and dry
  • Transportation: by sea or by air
  • LimitNum: 1 Kilogram

Superiority

Introduction     

Abiraterone acetate, the active ingredient of ZYTIGA is the acetyl ester of abiraterone. Abiraterone is an inhibitor of CYP17 (17α-hydroxylase/C17,20-lyase). Each ZYTIGA tablet contains 250 mg of abiraterone acetate. Abiraterone acetate is designated chemically as (3β)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate

Abiraterone acetate is a white to off-white, non-hygroscopic, crystalline powder. Its molecular formula is C26H33NO2and it has a molecular weight of 391.55. Abiraterone acetate is a lipophilic compound with an octanol-water partition coefficient of 5.12 (Log P) and is practically insoluble in water. The pKa of the aromatic nitrogen is 5.19.

Inactive ingredients in the tablets are colloidal silicon dioxide, croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone, and sodium lauryl sulfate.

English name: Abiraterone acetate

Synonyms:Abirateroneacetate;CB 7630;(3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-yl acetate

Specification: 98%

CAS NO.:154229-18-2

Appearance: White crystalline powder

Molecular weight: 391.55

Molecular formula:C26H33NO2

Function      

Abiraterone is a drug used in castration-resistant prostate cancer. It is formulated as the prodrug abiraterone acetate. Abiraterone can be used as a prostate cancer drug treatment. Abiraterone is a inhibitor of CYP17. It can be used to treat CRPC.

 

Application      
Abiraterone is used as pharmaceutical raw material.

Specification

Item

Specification

Result

Appearance

White crystalline powder

Complies

Related substance (HPLC)

Total impurity 0.5%

Max single impurity 0.1%

0.2%

0.06%

Odor

Characteristic

Complies

Assay

99%

99.8%

Sieve analysis

100% pass 80 mesh

Complies

Loss on Drying

Residue on Ignition

≤1.0%

≤1.0%

0.12%

0.09%

Heavy Metal

<10ppm

Complies

As

<0.1ppm

0.05ppm

Pb

<0.1ppm

0.05ppm

Cd

<0.1ppm

0.05ppm

Residual Solvents

<100ppm

Complies

Residual Pesticide

Negative

Complies

Microbiology

 

 

Total Plate Count

<1000cfu/g

Complies

Yeast & Mold

<100cfu/g

Complies

E.Coli

 

Details

Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries. 

The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Pioneer. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis. 

With our phytopharmaceutical background and knowledge through experience, PIONEER can also provide a wide range of analytical services and reference substances to our clients. In addition, We also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: SAM-e Tosylate Disulfate; SAM-e 1,4-Butanedisulfonate; Polycytidylic Acid; Polyinosinic Acid; Adenosine Triphosphate Disodium; and Cytidine Triphosphate Disodium; these items are our strongest advantage in China. Meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry. 

Recently, Kono Chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. As a GMP standardized manufacturer, our products can meet or even exceed the standards of CP2010, USP32, BP2005 and EP4. Presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as USA, EU, South America and Southeast Asia. There are experienced technicians working for our institutes now, all of them are skilled. Pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.

 

Other products of this supplier

Kono Chem Co.,LtdTel:86-29-86107037-8015 Fax:86-29-81330164  Email:info@konochemical.com
 Address:No.11 Daqing Road,Lianhu District,Xi’an 710082,China,710082