Menaquinone 7 belongs to a class of K2-vitamin homologs originally discovered as the anti-hemorrhagic factors. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins, such as osteocalcin and matrix-Gla protein, which play crucial roles in building and maintaining overall bone health. Menaquinone 7 is found in a variety of fermented foods. In vivo, Menaquinone 7 has been shown inhibiting aortic and myocardial calcification. In a rat model of extraosseous clacifciation, Menaquinone 7 decreased aortic alkaline phosphatase tissue concentrations.

Menaquinone 7 is a form of vitamin K2, which includes nine related compounds. Menaquinone 7 is a long-chain menaquinone that is synthesized by Escherichia coli bacteria in the gut. It can be used as a supplement for bone health. Menaquinone 7 can be used as vitamin supplement in health care products.

Menaquinones are isoprenoid quinones of the naphthalene series and belongs to the K2 Vitamin homologs. Menaquinones were originally discovered as the anti-hemorrhagic factor and now encompasses a vari ety of physiological processes. Menaquinone 7 belongs to the class of K2-Vitamins homologs. Menaquinone 7 has been identified as the most bioactive cofactor for the carboxylation reaction of Gla-prote ins such as osteocalcin and matrix-Gla protein, which plays a crucial role in building and maintaining overall bone health.