High Purity Salmon Calcitonin Acetate / Salmon Calcitonin CAS 47931-85-1 CAS NO.47931-85-1

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Product Details

Keywords

High Purity Salmon Calcitonin Acetate
47931-85-1
CAS 47931-85-1

Quick Details

ProName: High Purity Salmon Calcitonin Acetate ...
CasNo: 47931-85-1
Molecular Formula: C145H240N44O48S2
Appearance: white powder
Application: CAS 47931-85-1
DeliveryTime: prompt delivery after payment confirm...
PackAge: 25kg carton drum(32cm*58cm)or 1kg foi...
Port: any port in china
ProductionCapacity: 5000 Kilogram/Month
Purity: 99%
Storage: Sealed,light and oxygen resistant
Transportation: By sea & By air
LimitNum: 1 Kilogram
Plant of Origin: Jiangsu China (Mainland)
Testing Method: uv
Product Ecification: 99%
Heavy Metal: eppm
Voluntary Standards: usp
name: Salmon Calcitonin Acetate

Superiority

Superiority

pioneerbiotech is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals.

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3.mature Technical support
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Details

GMP and MDF certificated Salmon Calcitonin,CAS.:47931-85-1, in bulk supply ,welcome inquiry

Name

Salmon Calcitonin 47931-85-1

Accession Number

DB00017 (BIOD00025, BTD00025)

Type

biotech

Groups

approved

Description

Synthetic peptide, 32 residues long formulated as a nasal spray.

Protein structure

Protein chemical formula

C₁₄₅H₂₄₀N₄₄O₄₈S₂

Protein average weight

3431.8530

Sequences

>DB00017 sequence CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

FASTA

Synonyms

Calcitonin 1 precursor

Calcitonin-salmon

Calcitonin, salmon

Salmotonin

Salts

Not Available

Brand mixtures

Not Available

Categories

Antiosteporotic Agents
Bone Density Conservation Agents
Antihypercalcemic agent

CAS number

47931-85-1 thyrocalcitonin

Taxonomy

Kingdom

Not Available

Classes

Not Available

Substructures

Not Available

Pharmacology

Indication

For the treatment of post-menopausal osteoporosis

Pharmacodynamics

Calcitonin inhibits bone removal by osteoclasts (bone remodeling cells) and promotes bone formation by osteoblasts. This leads to a net increase in bone mass. Calcitonin also reduces plasma calcium levels and enhances secretion of ions in the kidney.

Mechanism of action

Calcitonin binds to the calcitonin receptor (found primarily in osteoclasts) which then enhances the production of vitamin D producing enzymes (25-hydroxyvitamine D-24-hydroxylase), leading to greater calcium retention and enhanced bone density. Binding of calcitonin to its receptor also activates adenylyl cyclase and the phosphatidyl-inositol-calcium pathway.

Absorption

Salmon calcitonin is rapidly absorbed and eliminated. Bioavailability following subcutaneous and intramuscular injection in humans is high and similar for the two routes of administration (71% and 66%, respectively).

Volume of distribution

Not Available

Protein binding

30 to 40%

Metabolism

Salmon calcitonin is primarily and almost exclusively degraded in the kidneys, forming pharmacologically inactive fragments of the molecule.

Route of elimination

Studies with injectable calcitonin show increases in the excretion of filtered phosphate, calcium, and sodium by decreasing their tubular reabsorption in the kidney.

Half life

50-80 minutes

Clearance

Not Available

Toxicity

Salmon calcitonin is devoid of embryotoxic, teratogenic and mutagenic potential.

Affected organisms

Humans and other mammals

About our company

Founded in 2014, as a professional international pharmaceutical corporation,

headquartered in Xi'an (China), KonoChemCo., Ltd. is a leading producer of

standardized herbal extracts, natural active ingredients and APIs for pharmaceutical,

health food and cosmetic industries.

Bulk Herbal Nutrients& Phytochemical Manufacture, Food Ingredients Supplier
The Most Favorable Price Best Quality
Please visit our website: www.konochemical.com

made In china/chemical/food grade raw material/vitamin B2/riboflavin, vitamin B2

5. Package of our products

made In china/chemical/food grade raw material/vitamin B2/riboflavin, vitamin B2

6.Extraction equipment

made In china/chemical/food grade raw material/vitamin B2/riboflavin, vitamin B2

7. Express Delivery

To know more about our products, please check the catalogue at below:

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009	Ursolic Acid	Eriobotrya japonica(Thunb.)Lindl	1%-98%	CP2010	Drum & Bag
010	Chlorogenic Acid	Eucommia ulmoides Oliv.	1%-98%	CP2010	Drum & Bag
011	Usnic Acid	Usneaceae	98%	CP2010	Drum & Bag
012	Shikimic Acid	Illicium verum Hook.f.)	98%	USP32	Drum & Bag
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