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favourable price of Arbutin in china 497-76-7 98%

favourable price of Arbutin in china 497-76-7 98% CAS NO.497-76-7

  • FOB Price: USD: 200.00-300.00 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,MoneyGram,Other
  • Available Specifications:

    TOP(1-10)KilogramTOP(10-100)Kilogram

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Keywords

  • Arbutin in china
  • favourable price of Arbutin
  • 497-76-7 98%

Quick Details

  • ProName: favourable price of Arbutin in china...
  • CasNo: 497-76-7
  • Molecular Formula: C12H16O7
  • Appearance: Solid powder
  • Application: Applied in dietary supplements,pharmac...
  • DeliveryTime: prompt
  • PackAge: Foil bag or drum
  • Port: Beijing or Guangzhou Port
  • ProductionCapacity: 5000 Kilogram/Month
  • Purity: 99% BY HPLC
  • Storage: Sealed,light and oxygen resistant
  • Transportation: by sea or air
  • LimitNum: 1 Kilogram
  • Plant of Origin: arbutin
  • Testing Method: hplc
  • Product Ecification: top
  • Heavy Metal: 1ppm
  • Voluntary Standards: CP2010
  • name: arbutin
  • CAS: 497-76-7

Superiority

Arbutin (β-arbutin) is a hydroquinone glycoside, which is accumulated in many plant species such as bearberry (Arctostaphylos uva-ursi L.), bergenia (Bergenia spp.) and myrothamnus (Myrothamnus flabellifolia Welw.). It has been reported that arbutine inhibits the oxidation of L-tyrosine in a competitive manner catalyzed by tyrosinase which is an oxidase that catalyzes the rate-limiting step in melanin (a group of natural pigments) biosynthesis. Arbutins (α- and β-arbutins) are widely used in the cosmetic industry.

Arbutin is a glycosylated hydroquinone that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, and anti-inflammatory properties. It inhibits human tyrosinase activity in crude tyrosinase solution isolated from human melanocytes (IC50s = 5.7 and 18.9 mM using L-tyrosine and L-DOPA as substrates, respectively) as well as in intact melanocytes (IC50 = 0.5 mM). Arbutin (50 μM) inhibits hemolysis induced by the free radical generator AAPH in sheep erythrocytes and inhibits AAPH-induced decreases in cell viability in cultured human skin fibroblasts when used at concentrations greater than 125 μM. In an LPS-induced rat model of acute lung injury, arbutin (50 mg/kg) prevents increases in IL-1β, IL-6, and TNF-α levels in lung tissue and serum. Formulations containing arbutin have been used in the treatment of hyperpigmentation disorders.

Details

arbutin is used primarily for its anti-oxidant and bleaching properties. Arbutin is the active constituent of bearberry, and found in other plant sources, including wheat. It acts as a tyrosinase inhibitor by converting to hydroquinone, and thus can prevent melanin formation.

Cat. No. A1470000
CAS. No. 497-76-7
Molecular Formula C12H16O7
Formula Weight 272.25 g/mol
Synonyms p-Arbutin
Chemical Name 4-Hydroxyphenyl-β-D-glucopyranoside; Hydroquinone β-D-glucopyranoside
Category Working Standards
Product Stock Status Please Enquire

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Kono Chem Co.,LtdTel:86-29-86107037-8015 Fax:86-29-81330164  Email:info@konochemical.com
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