China (Mainland)
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83-67-0 discount Theobromine factory CAS NO.83-67-0
- FOB Price: USD: 100.00-100.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
- Available Specifications:
99%(10.0000-25.0000)Kilogram
- Product Details
Keywords
- Theobromine
- Theobromine factory
- 83-67-0 discount
Quick Details
- ProName: 83-67-0 discount Theobromine factory
- CasNo: 83-67-0
- Molecular Formula: C7H10N4O2
- Appearance: solid or liquid
- Application: for pharma use
- DeliveryTime: prompt
- PackAge: drum and bag
- Port: Beijing or Guangzhou Port
- ProductionCapacity: 5000 Kilogram/Month
- Purity: 99.90%
- Storage: in sealed air resistant place
- Transportation: by sea or air
- LimitNum: 1 Kilogram
- Grade: Food Grade，Pharma Grade
- Appearance: Brown fine powder
Superiority
Phosphosdiesterase inhibitor, weak adenosine receptor antagonist, diuretic and smooth muscle relaxant.
Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist Theobromine (150 μg/ml) increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium. It inhibits decreases in renal cortex SIRT1 activity and increases in NADPH oxidase-dependent reactive oxygen species (ROS) production, as well as reduces kidney hypertrophy and albuminuria in a spontaneously hypertensive rat model of streptozotocin-induced diabetes when administered at a dose of 5 mg/kg per day. Theobromine is toxic to dogs with an LD50 value of 250 to 500 mg/kg.
Details
Theobromine is a weak PDE (phosphodiesterase) inhibitor and Adenosine A Receptor (adenosine receptor) blocker as well as a diuretic and smooth-muscle relaxant.
| Catalogue Number | T343800 |
| Chemical Name | Theobromine |
| Synonyms | 3,7-Dihydro-3,7-dimethyl-1H-purine-2,6-dione; 3,7-Dimethyl-3,7-dihydro -1H-purine-2,6-dione; 3,7-Dimethylxanthine; Diurobromine; NSC 5039; SC 15090; Santheose; Teobromin; Theosalvose; Theostene; Thesal; Theophylline-Ethylenediamine Imp. G (EP) |
| CAS Number | 83-67-0 |
| Molecular Formula | C?H?N?O? |
| Appearance | White to Off-White Solid |
| Melting Point | >300°C (dec.) |
| Molecular Weight | 180.16 |
| Storage | Refrigerator |
| Solubility | Chloroform (Very Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Sonicat |
| Category | Standards; Food; |
| Applications | A metabolite of Caffeine. |