Gamma cyclodextrin is an 8 glucose units composed of end to end cyclic compounds, compared with beta cyclodextrin, whice has a larger diameter cavity(about 1.3 times cyclodextrin), cavity volume (about 1.6 times more beta cyclodextrin), better solubility in water (12.5 times the cyclodextrin cavity) and a better fit (no ring hydrogen bond, non rigid ring). Therefore, Gamma cyclodextrin has more potential application than beta cyclodextrin.Gamma cyclodextrin water solubility is 23.2g/100ml (25 DEG C), in some cases the solubility still limits the application .

Hydroxypropyl gamma cyclodextrin's water solubility increase to 80g/100ml (25 C) furtherly , and hydropropyl gamma cyclodextrin is no longer a single pure product but the coexistence of multiple substituted compounds, with guest molecules when wrapping is not easy to generate inclusion crystallization. Overall, hydroxypropyl - gamma cyclodextrin has a higher solubility in water and  stronger  anti crystallization ability.     

Name: hydrxypropyl- gamma-cyclodextrin   

Other name : hydroxypropyl-γ-cyclodextrin ; gamma-Cyclodextrin 2-hydroxypropyl ethers;(2-Hydroxyapropyl)-gamma-cyclodextrin.

Abbreviation : HPGCD

CAS No.: 128446-34-4

Molecular structuer:

Molecular formula : C48H80-nO40.(C3H7O)n

Molecular weight: 1297.2+n.(58.1)

Grade : pharma grade

Solubility(in 100cm3 solvent, at 25℃) :   water:      >50g

                                                                         Methanol:  >50g

                                                                        Chloroform:  <1.0g

Qaulity : injection grade / pharma grade / chemical grade 

Standard : enterprise standard 

Package: 500g/bag , 2kg/bag,  10kg/drum or customized

Use : medical \ chemical 

Storage: at room temperature, in tightly closed container.

Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries. 

The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Pioneer. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis. 

With our phytopharmaceutical background and knowledge through experience, PIONEER can also provide a wide range of analytical services and reference substances to our clients. In addition, We also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: SAM-e Tosylate Disulfate; SAM-e 1,4-Butanedisulfonate; Polycytidylic Acid; Polyinosinic Acid; Adenosine Triphosphate Disodium; and Cytidine Triphosphate Disodium; these items are our strongest advantage in China. Meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry. 

Recently, Kono Chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. As a GMP standardized manufacturer, our products can meet or even exceed the standards of CP2010, USP32, BP2005 and EP4. Presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as USA, EU, South America and Southeast Asia. There are experienced technicians working for our institutes now, all of them are skilled. Pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.