CAS:170729-80-3 Aprepitant CAS NO.170729-80-3

Min.Order: 1 Kilogram
Payment Terms: T/T,Other

Product Details

Keywords

Aprepitant
Aprepitant high purity
5-[2(R)-[1(R)-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)morpholin-4-ylmethyl]-3,4-dihydro-2H-1,2,4-triazol-3-one

Quick Details

ProName: CAS:170729-80-3 Aprepitant
CasNo: 170729-80-3
Molecular Formula: C10H14ClNO2
Appearance: White powder
Application: Pharmaceuticals
DeliveryTime: within 3-4days after received your pay...
PackAge: according to customers' requirements
Port: all chinese port
ProductionCapacity: 100 Kilogram/Month
Purity: 99.5%
Storage: store in cool and dry
Transportation: by sea or by air
LimitNum: 1 Kilogram
Related Substances: Desfluoro aprepitant NMT 0.15%
Heavy Metal: ≤10ppm
Valid Period: 2019-9-10

Superiority

We Puhopharma supply high quality of good pharmaceutical product. We specialize in controling the quality and reducing the impurities of Aprepitant .

Our Aprepitant is with the best quality and the most competitive price in China. Our Aprepitant reaches USP standard.

COA of our Aprepitant

Product Name	Aprepitant; 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)m orpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one
Batch No.	86-42-5	Retest date		July, 2014
Quantity	6.0kg	Manu. date		Aug. 2012
Storage	Preserve in well-closed containers, protected from light. Store at room temperature.	Analysis date		July.15, 2013
Cas:	170729-80-3	Catalog No.		AP0600

Item	Specification		Test Results
Description	Off-white to light yellow powder		Conforms
Identification IR	HPLC, IR		Conform
Specific optical rotation	+68.0° ±3° (c=1.0, in Methanol)		67.49°
Melting point	248±5 °C		248 -250°C
Water	≤0.5%		0.29%
Heavy metals	≤10ppm		Conforms
Residue on ignition	Not more than 0.1%		0.07%
Related substances	Desfluoro aprepitant NMT 0.15% R,R,R-Diastereomer: NMT 0.15% Any other individual impurity: NMT 0.10% Total impurities: NMT 0.50%		0.09% 0.08% 0.06% 0.29%
Enantiomer purity	NMT 0.15% of the S,R,S-enantiomer		0.07%
Assay (HPLC)	NLT 98.0% and NMT 102.0% (on the anhydrous basis)		99.9%
Organic volatile impurities	Methanol NMT 2500 ppm; Xylene NMT 2170 ppm; Toluene NMT 890 ppm; DMSO NMT 5000ppm		Conforms
Conclusion: Conforms to Authorized USP Pending Monograph

Details

Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.

The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Pioneer. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.

With our phytopharmaceutical background and knowledge through experience, PIONEER can also provide a wide range of analytical services and reference substances to our clients. In addition, We also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: SAM-e Tosylate Disulfate; SAM-e 1,4-Butanedisulfonate; Polycytidylic Acid; Polyinosinic Acid; Adenosine Triphosphate Disodium; and Cytidine Triphosphate Disodium; these items are our strongest advantage in China. Meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry.

Recently, Kono Chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. As a GMP standardized manufacturer, our products can meet or even exceed the standards of CP2010, USP32, BP2005 and EP4. Presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as USA, EU, South America and Southeast Asia. There are experienced technicians working for our institutes now, all of them are skilled. Pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.