Superiority

kono chem is a leading manufacturer and supplier of chemicals in China. 

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and other fine chemicals. 

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Company information

Founded in 2012 as a professional international pharmaceutical corporation, headquartered in Xi'an (China), Xi'an Konochemical Co., Ltd, is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.

Basic information

Product name: Tetrahydropalmatine

CAS No. 2934-97-6 

Molecular formula: C21H25NO4

Molecular weight: 355.42

Specification: Tetrahydropalmatine≥98%HPLC

Appearance: Light yellow to white crystal powder

Brand: Rongsheng

Storage: In cool,dry and clean.

Shelf life: 2 years.

Description:

Tetrahydropalmatine (THP) is an alkaloid found in several different plant species, mainly in the Corydalis family, but also in other plants such as Stephania rotunda. These plants have traditional uses in Chinese herbal medicine. The pharmaceutical industry has synthetically produced the more potent enantiomer Levo-tetrahydropalmatine (Levo-THP), which has been marketed worldwide under different brand names as an alternative to anxiolytic and sedative drugs of the benzodiazepine group and analgesics such as opiates. It is also sold as a dietary supplement.

Tetrahydropalmatine has been demonstrated to possess analgesic effects and may be beneficial in the treatment of heart disease and liver damage. It has also shown useful effects in the treatment of drug addiction to both cocaine and opiates, and preliminary human studies have shown promising results.

Animal experiments have shown that the sedative effect of tetrahydropalmatine results from blocking dopaminergic neurons in the brain. Dopamine is one of the most important neurotransmitters in the central nervous system where it occurs in several important systems that regulate muscular activity and attention, as well as feelings of joy, enthusiasm and creativity. Therefore,tetrahydropalmatine causes no feelings of euphoria, and has been seen as an alternative to addictive drugs for people suffering from anxiety and pain, and as a possibility for relief for people not helped by existing drugs.

Specification:

Function

-Tetrahydropalmatine has the protective effect on liver injury induced by carbon tetrachloride in mice.

-Tetrahydropalmatine have analgesia and sedative-hypnotic activity, can depress the chtonic persistent pain and splanchna dull pain.

-Tetrahydropalmatine has effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain.

-Tetrahydropalmatine is often used for hypochondriac pain due to stagnation of the liver-qi, stomachache due to stagnation of the stomach-qi, hernial pain.

Application

(1) Pharmaceutical

(2) Cosmetics