Fucoxanthin is a carotenoid that occurs naturally in certain algae. It significantly reduces abdominal white adipose tissue (WAT) in mice and rats when included in their diet. Fucoxanthin increases the amount of mitochondrial uncoupling protein 1 (UCP1), a fatty acid-stimulated protein involved in respiration and thermogenesis in WAT of mice and rats. In KK-Ay mice, which are used to model obese type 2 diabetics with hyperinsulinemia, fucoxanthin reduces WAT gain and also decreases blood glucose and plasma insulin levels.

Fucoxanthin is a kind of natural pigments belonging to lutein-class in carotenoids class, accounting for over 10% of the total amount of carotenoids which contains 700 species of naturally occurring species. Its color is pale yellow to brown and it is belongs to the pigment being contained in brown algae, diatoms, golden algae and green and yellow algae. It is widely distributed among a variety of algae, marine phytoplankton, shellfish and other aquatic plants and animals. It has various pharmaceutical effects such as anti-tumor, anti-inflammatory, anti-oxidant, causing weight loss, protecting nerve cell, increasing the content of ARA(arachidonic acid) and DHA (docosahexaenoic acid) in mice; it is widely spread in market of skin care, cosmetics product and the health care.

Fucoxanthin is a carotenoid that occurs naturally in certain algae. It significantly reduces abdominal white adipose tissue (WAT) in mice and rats when included in their diet. Fucoxanthin increases the amount of mitochondrial uncoupling protein 1 (UCP1), a fatty acid-stimulated protein involved in respiration and thermogenesis in WAT of mice and rats. In KK-Ay mice, which are used to model obese type 2 diabetics with hyperinsulinemia, fucoxanthin reduces WAT gain and also decreases blood glucose and plasma insulin levels.

Trustworthy Manufacturer Supply High Purity 3351-86-8 with Competitive Price

• Molecular Formula:C₄₂H₅₈O₆
• Molecular Weight:658.919
• Appearance/Colour:Crystalline solid 
• Melting Point:166-168 °C 
• Refractive Index:1.563 
• Boiling Point:764.1 °C at 760 mmHg 
• PKA:14.47±0.60(Predicted) 
• Flash Point:223 °C 
• PSA：96.36000 
• Density:1.09 g/cm³ 
• LogP:8.69220 

Fucoxanthin(Cas 3351-86-8) Usage

Biochem/physiol Actions	Xanthophyll carotenoid pigment extracted from algae. Exhibits anticancer, antioxidant, anti-obesity and anti-inflammatory properties.
Definition	ChEBI: A natural product found in Sporochnus comosus.
General Description	Fucoxanthin is isolated from brown algae. It has anti-angiogenic, hepatoprotective,?cardiovascular and cerebrovascular protective properties. Fucoxanthin stimulates G1 cell-cycle arrest and apoptosis in cancer cell lines.

InChI:InChI=1/C42H60O7/c1-29(18-14-19-31(3)22-23-37-38(6,7)26-35(49-33(5)43)27-40(37,10)46)16-12-13-17-30(2)20-15-21-32(4)36(45)28-42(48)39(8,9)24-34(44)25-41(42,11)47/h12-22,34-35,44,46-48H,24-28H2,1-11H3/b13-12+,18-14+,20-15+,29-16+,30-17+,31-19+,32-21+/t23-,34-,35-,40+,41+,42-/m0/s1

3351-86-8 Relevant articles

Application of diphenyl diselenide as a new catalyst for photochemical stereoisomerization of carotenoids

Strand, Aase,Liaaen-Jensen, Synnove

, p. 1263 - 1269 (2007/10/03)

In a comparative study, diphenyl diselen...

Carotenoids and related polyenes. Part 3. First total synthesis of fucoxanthin and halocynthiaxanthin using oxo-metallic catalyst

Yamano, Yumiko,Tode, Chisato,Ito, Masayoshi

, p. 1895 - 1904 (2007/10/02)

The first total synthesis of optically a...

Total synthesis of photosynthetic pigment fucoxanthin by use of oxo- metallic catalyst

Yamano,Ito

, p. 410 - 412 (2007/10/02)

The first total synthesis of optically a...

3351-86-8 Process route

Acetic acid (1S,3R)-3-hydroxy-4-[(3E,5E,7E,9E,11E,13E,15E)-18-((R)-4-hydroxy-2,6,6-trimethyl-cyclohex-1-enyl)-3,7,12,16-tetramethyl-17-oxo-octadeca-1,3,5,7,9,11,13,15-octaenylidene]-3,5,5-trimethyl-cyclohexyl ester

3351-86-8,17257-05-5,55659-36-4,55659-37-5,55659-38-6,92761-37-0,124378-42-3,138126-73-5,141270-13-5,141270-14-6,141270-15-7,141270-16-8

fucoxanthin

Acetic acid (1S,3R)-3-hydroxy-4-[(3E,5E,7E,9E,11E,13E,15E)-18-((1R,4S,6S)-4-hydroxy-2,2,6-trimethyl-7-oxa-bicyclo[4.1.0]hept-1-yl)-3,7,12,16-tetramethyl-17-oxo-octadeca-1,3,5,7,9,11,13,15-octaenylidene]-3,5,5-trimethyl-cyclohexyl ester

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid;	28% 8%
With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 1h; Yield given;

3351-86-8,17257-05-5,55659-36-4,55659-37-5,55659-38-6,92761-37-0,124378-42-3,138126-73-5,141270-13-5,141270-14-6,141270-15-7,141270-16-8

fucoxanthin

Conditions

Conditions	Yield
With iodine; for 8h; Irradiation; sunlight;

3351-86-8 Downstream products

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  3351-87-9

  fucoxanthin monoacetate

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  fucoxanthinol