- Product Details
Keywords
- Trimethoprim
- Trimethoprim
- 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
Quick Details
- ProName: CAS:738-70-5 Trimethoprim
- CasNo: 738-70-5
- Molecular Formula: C14H18N4O3
- Appearance: White powder
- Application: Medicine
- DeliveryTime: within 3-4days after received your pay...
- PackAge: according to customers' requirements
- Port: all chinese port
- ProductionCapacity: 100 Kilogram/Week
- Purity: 99.5%
- Storage: store in cool and dry
- Transportation: by sea or by air
- LimitNum: 1 Kilogram
Superiority
Chemical Name: Trimethoprim (TMP)
Other name:
Abaprim;5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine;5-(3,4,5-trimethoxybenzyl)-2,4-diaminopyrimidine
CAS: 738-70-5
EINECS No.: 212-006-2
Formula: C14H18N4O3
Molecular Weight: 290.32
Purity: 99.8%
Appearance: White or yellowish-white powder
BP/USP Pharmaceutical
Function:
antibacterial drug efficiency, separate for respiratory tract infections, urinary tract infections,intestinal infections and other illnesses. Range and similar antibacterial sulfonamides, in combination with sulfa drugs or in combination with antibiotics, can significantly improve drug efficacy. For respiratory tract infections, senile chronic bronchitis, dysentery, urinary tract infection, pyelonephritis, enteritis, typhoid, gonorrhea, and some of the specific disease and other inflammation.
Application:
Cure pneogaster infection, chronic senile bronchitis, bacillary dysentery, urinary tract infection, pyelon-dphristis, enteritis typhoid, gonorrhea and some specific lesion etc
Specification:
Items |
Standard |
Results |
||
Appearance |
White or yellowish-white powder |
White powder |
||
Solubility |
Very slightly soluble in water, slightly soluble in alcohol. |
Very slightly soluble in water, slightly soluble in alcohol. |
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•Identification |
||||
A: Melting point |
199-203 |
201.0-201.4 |
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B: Specific absorbance |
Max.287nm: 240-250 |
243 |
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C: IR-spectrum |
Complies with reference spectrum |
Complies with reference spectrum |
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D: Chemical reaction |
Green fluorescence at 365nm |
Green fluorescence at 365nm |
||
Appearance of solution |
Not more intensely colored than Reference Solution BY7 |
Less intensely colored than reference solution BY7 |
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Related substances |
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Method A by HPLC: |
|
|
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Impurity F |
≤0.1% |
0.05% |
||
Any single impurity |
≤0.1% |
<0.1% |
||
Total impurities |
≤0.2% |
<0.2% |
||
Method B by HPLC: |
|
|
||
Any single impurity |
≤0.1% |
<0.1% |
||
Total impurities |
≤0.2% |
<0.2% |
||
Heavy metals |
≤20ppm |
< 20ppm |
||
Residual methanol |
≤3000ppm |
Not detected |
||
Residual DMSO |
≤5000ppm |
Not detected |
||
Residual acetic acid |
≤5000ppm |
Not detected |
||
Impurity K(aniline) by GC |
≤5ppm |
Not detected |
||
Loss on drying |
≤0.5% |
0.3% |
||
Sulphated ash |
≤0.1% |
0.02% |
||
Assay |
98.5-101.0% |
99.71% |
||
Particle size |
100% pass 300 mesh |
100% pass 300 mesh |
Details
Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.
The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Pioneer. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.
With our phytopharmaceutical background and knowledge through experience, PIONEER can also provide a wide range of analytical services and reference substances to our clients. In addition, We also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: SAM-e Tosylate Disulfate; SAM-e 1,4-Butanedisulfonate; Polycytidylic Acid; Polyinosinic Acid; Adenosine Triphosphate Disodium; and Cytidine Triphosphate Disodium; these items are our strongest advantage in China. Meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry.
Recently, Kono Chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. As a GMP standardized manufacturer, our products can meet or even exceed the standards of CP2010, USP32, BP2005 and EP4. Presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as USA, EU, South America and Southeast Asia. There are experienced technicians working for our institutes now, all of them are skilled. Pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.