English name: Methylprednisolone

Molecular Formula:C22H30O5
Molecular Weight:374.4706
CAS Registry Number:83-43-2
EINECS:201-476-4
Quality:BP/CP

Density:1.28g/cm3
Melting point:228-237°C (dec.)
Boiling point:571.8°C at 760 mmHg
Refractive index:1.602
Flash point:313.7°C
Vapour Pressur:1.86E-15mmHg at 25°C 

Methylprednisolone is a synthetic glucocorticoid or corticosteroid drug.

 It is marketed in the USA and Canada under the brand names Medrol and SoluMedrol.

It is also available as a generic drug.It is a variant of prednisolone, methylated at carbon 6 of the B ring.

Function                                                  

1-Like most adrenocortical steroids, methylprednisolone is typically used for its anti-inflammatory effects;

2-Methylprednisolone is also prescribed for nonpenetrating spinal cord injuries;

3-Common uses include arthritis therapy and short-term treatment of bronchial inflammation or acute bronchitis due to various respiratory diseases;

4-Methylprednisolone can also used for vestibular neuritis;

5Methylprednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for

which they have a high 

Application                                             

1-Applied in pharmaceutical field, It is used both in the treatment of acute periods and long-term management of autoimmune diseases, most notably systemic lupus erythematosus;

2-It is also used as a treatment for multiple sclerosis.

Specification                                          

Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries. 

The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Pioneer. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis. 

With our phytopharmaceutical background and knowledge through experience, PIONEER can also provide a wide range of analytical services and reference substances to our clients. In addition, We also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: SAM-e Tosylate Disulfate; SAM-e 1,4-Butanedisulfonate; Polycytidylic Acid; Polyinosinic Acid; Adenosine Triphosphate Disodium; and Cytidine Triphosphate Disodium; these items are our strongest advantage in China. Meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry. 

Recently, Kono Chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. As a GMP standardized manufacturer, our products can meet or even exceed the standards of CP2010, USP32, BP2005 and EP4. Presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as USA, EU, South America and Southeast Asia. There are experienced technicians working for our institutes now, all of them are skilled. Pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.

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