Ceramides, known as sphingolipids, play an important role in the formation of the outermost layer of skin. They are the main constituent (>50%) present in the intercellular spaces of the stratum corneum and protect against external irritants and reduce TEWL. When there is a loss of ceramides in the skin, there can be a high level of water loss, which leads to dry skin and irritation.

The ceramides mixture consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides are generated from sphingomyelin through activation of sphingomyelinases or through the de novo synthesis pathway, which requires the coordinated action of serine palmitoyl transferase and ceramide synthase. They have been shown to mediate antiproliferative responses such as apoptosis, growth arrest, differentiation, and senescence.

ceramides is a family of naturally occurring lipids that act primarily in the skin’s uppermost layer, forming a protective barrier and reducing natural transepidermal water loss. Ceramides repair the stratum corneum layer in cases of dry skin, improve skin hydration, and increase the feeling of softness. They are beneficial for stressed, sensitive, scaly, rough, dry, aged, and sun-damaged skin. Ceramides play an essential role in the structure of superficial epidermal layers and form an integral part of the intercellular membrane network. They help generate and sustain the skin’s barrier function. This is extremely important: if the stratum corneum’s hydration is maintained, then it functions more normally in terms of flexibility and desquamation, its integrity is upheld, and the skin is less susceptible to irritation. Ceramide production decreases with age, accentuating any tendency to dry skin. When incorporated into a skin care preparation, the topical application of ceramides could benefit the stratum corneum if the ceramides manage to fill the intercellular spaces and if they are hydrolyzed by the correct extracellular enzymes on the skin. Such application also can stimulate ceramide production in the skin, thereby increasing the skin’s natural lipid content and reinforcing the skin’s protective barrier, measured through transepidermal water loss. Topically applied ceramides have been shown to capture and bind water, necessary for the skin to remain supple, smooth, and hydrated. natural ceramides are obtained from animals and plants. While ceramides can be synthetically manufactured, it is hard to obtain an identical equivalent to those found in nature, making them expensive raw materials.

Cosmetics grade

1. Ceramide is a moisturizer newly developed in recent years.
2. Ceramide is a fat-soluble substance that constitutes the physical structure of the stratum corneum of the skin.
3. Ceramide can quickly penetrate the skin and form a network structure to lock in water.
4. Ceramide will decrease with age, resulting in dry skin, rough skin and other abnormal symptoms. Therefore, supplementing with ceramide is an ideal way to keep the skin young.

Functional food grade

1. Ceramide is absorbed by the small intestine, transferred into the blood, and then transferred into the body.
2. It makes the skin cells have good recovery and regeneration ability without affecting the body’s own nerv acid biosynthesis.