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L-5-Methyltetrahydrofolate calcium / L-5-MTHF CAS 151533-22-1 CAS NO.151533-22-1
- FOB Price: USD: 1.00-10.00 /Gram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,
- Available Specifications:
99%(1-100)Gram99%(101-999)Gram
- Product Details
Keywords
- L-5-Methyltetrahydrofolate calcium
- 151533-22-1
- L-5-MTHF
Quick Details
- ProName: L-5-Methyltetrahydrofolate calcium / L...
- CasNo: 151533-22-1
- Molecular Formula: 956.97372
- Appearance: Solid powder
- Application: Applied in dietary supplements,pharmac...
- DeliveryTime: prompt
- PackAge: Foil bag or drum
- Port: Beijing or Guangzhou Port
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99% BY HPLC
- Storage: Sealed,light and oxygen resistant
- Transportation: by sea or air
- LimitNum: 1 Kilogram
- Related Substances: 1.0%
- Residue on Ignition: 0.1%
- Heavy Metal: 10PPM
- Valid Period: 2 years
- Product Name: L-5-Methyltetrahydrofolate calcium
- Test method: HPLC
- CAS: 151533-22-1
- Appearance: White to light yellow powder
- Specification: 99%
- Shelf life: 2 years
- MF: C40H48CaN14O12
- MW: 956.97372
- Melting point: >300°C
Superiority
Superiority
kono chem is a leading manufacturer and supplier of chemicals in China.
We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals
and other fine chemicals.
We could give you:
1.Best quality in your requirement
2.Competitive price in China market
3.mature Technical support
4.Professional logistic support
All we want is win-win business. Send yr. inquiries, you will get it!
Company information
Founded in 2012 as a professional international pharmaceutical corporation, headquartered in Xi'an (China), Xi'an Konochemical Co., Ltd, is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.
Annually, more than 3,000 tons of a wide range of herbal extracts and natural active substances are extracted at Xi'an Konochemical Co.,Ltd manufacturing plant near Xi'an, China. These extracts are in compliance with worldwide GMP norms, international Pharmacopoeias, and international regulations.
The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Konochemical. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.
Details
L-5-Methyltetrahydrofolate calcium / L-5-MTHF CAS 151533-22-1
Introduction
Product name: L-5-Methyltetrahydrofolate calcium
Synonym(s) :
L-5-Methyltetrahydrofolic acid, calcium salt
L-Methyltetrahydrofolate, calcium salt
L-Methylfolate, calcium
L-5-MTHF-Ca
Other name:CALCIUML-5-METHYLTETRAHYDROFOLATE; L-5-MTHF-Ca ; (6S)-N-[4-(2-Amino-1,4,5,6,7,8,-hexahydro-5-methyl-4-oxo-6-pteridinylmethylamino)benzoyl]-L-glutaminsure,Calciumsalz (1:1); L-5Methyltetrahydrofolic acid,
calcium salt; L-Methyltetrahydrofolate,calcium salt; L-Methylfolate, calcium; L-5-MTHF-Ca; Calcium levomefolate
CAS#:151533-22-1
Appearance:Off-White to Pale Yellow Solid
Assay:98.0Min.
Mol.Formula:C20H23CaN7O6
Melting Point: >300°C
Mol.Weight:497.5179
Function
1. mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdose treatment caused severe toxic effects.
2. folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused by poor.
3. as adjuvant therapy for colon cancer, rectal cancer.
4. combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors. High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.
5. for children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued.
Application
The calcium salt of L-5-methyltetrahydrofolic acid which belongs to the group of folate vitamins (Vitamin B9, Folacin).
It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.
Specification
|
ITEM |
SPECIFICATION |
|
|
Physical |
Appearance |
White to yellowish powder |
|
Identification |
IR-spectrum and HPLC retention time comply with that of the reference standard, calcium positive |
|
|
Specific Rotation (C=1.5%in water,25℃) |
+38.0~+42.00 |
|
|
Calcium(Anhydrous basis) |
7.0%-8.5% |
|
|
Sulfate |
≤0.015% |
|
|
Chloride |
≤0.021% |
|
|
Water (K-F) |
≤17.0% |
|
|
Chemical |
Heavy metals (Pb) |
≤10ppm |
|
Arsenic (As2O3) |
≤1ppm |
|
|
D-5-Methylfolate |
NMT 1.0% |
|
|
Assay |
Assay (HPLC) |
98.0%~103.0% |
|
Microorganism |
Total plate count |
≤1000cuf/g |
|
Mold & Yeasts |
≤100cuf/g |
|
|
Salmonella |
Negative |
|
|
E. Coil |
Negative |
|
|
Else |
Storage condition |
Store in sealed containers at cool & dry place. protect from light,moisture and pest infestation. |
|
Shelf life |
Two years when properly stored. |
|
25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
Blue plastic drum / Galvanized steel drums/ 200kg Iron drum or 25kg plastic bucket
Founded in 2012 as a professional international pharmaceutical corporation, headquartered in Xi'an (China), Xi'an Konochemical Co., Ltd, is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.
Annually, more than 3,000 tons of a wide range of herbal extracts and natural active substances are extracted at Xi'an Konochemical Co.,Ltd manufacturing plant near Xi'an, China. These extracts are in compliance with worldwide GMP norms, international Pharmacopoeias, and international regulations.
The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Konochemical. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.
Kono Chem is headquarted in Xi’ an Shaanxi Province, China, with convenient transportation access, covering an area of 312, 000 square meters, and technicians accounted for 35% of the total employees. Presently, we have two chemical fermentation plant, one test reaction plant, and one Provincial Research and Development Center now. Our well-equipped facilities and excellent quality control throughout production enables us to guarantee customer satisfaction. We insist in innovation and produce high quality products. And our workshops are GMP standard.
We also have strong professional research and development team, talented personnel and completely equipped laboratory for the quality controlling. Various Detection Devices are equipped, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
From the very beginning, we strictly manage our production according to the international standard like ISO9000,ISO14001, now has received the recogonition from costomers all over the world and has passed the audit by authoritative labs. At present, our products are mainly related to Biopharmaceuticals, Health Care Products, Cosmetic Ingredients, APIs, Intermediates, as well as some custom synthesis products.
Thanks to our EHS management system and high quality control, now 85% of our products are well-selling and appreciated in almost 50 countries all over the world, and established long-term cooperative business relationship with multinational companies such as CIPLA,BIOCON,DSM.
Yoyo
Email: sales3@konochemical .com
Web: www.konochemical.com
Address :11 Daqing Road, Xi’an,Shaanxi 710082, P.R China
KONO Chem Co., Ltd