Factory Supply Top Quality 16009-13-5 with Reasonable Price Hemin CAS NO.16009-13-5

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ProName: favourable price of Hemin 16009-13-5 ...
CasNo: 16009-13-5
Molecular Formula: C34H32ClFeN4O4
Appearance: Solid , powder
Application: for pharma use CAS 16009-13-5
DeliveryTime: Prompt
PackAge: drum and bag
Port: Beijing or Guangzhou
ProductionCapacity: 3000 Kilogram/Month
Purity: 99.90%
Storage: in sealed air resistant place
Transportation: by sea or air
LimitNum: 1 Kilogram
Related Substances: NMT0.001%
Residue on Ignition: 0.00%
Heavy Metal: NMT1PPM
Valid Period: 2 years
Product name: Chloroprotoferrihem
Purity: 98%
CAS: 16009-13-5

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Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries.

Annually, more than 3,000 tons of a wide range of herbal extracts and natural active substances are extracted at the Kono Chem Co.,Ltd manufacturing plant near Xi'an, China. These extracts are in compliance with worldwide GMP、HACCP norms, international Pharmacopoeias, and international regulations.
The botanical raw materials are subject to strict selection and inspection, and extracts are manufactured according to methods developed by Kono Chem. They include inspections to guarantee a high quality standard from both analytico-chemical and therapeutic points of view, and take into consideration the state of art in different fields: research and development, analyses, processes and machinery, therapeutic applications on a scientific basis.

With our phytopharmaceutical background and knowledge through experience, Kono Chem can also provide a wide range of analytical services and reference substances to our clients. In addition, We also manufacture pharmaceutical raw materials of nucleotide species, mainly including as below: SAM-e Tosylate Disulfate; SAM-e 1,4-Butanedisulfonate; Polycytidylic Acid; Polyinosinic Acid; Adenosine Triphosphate Disodium; and Cytidine Triphosphate Disodium; these items are our strongest advantage in China. Meanwhile, we can do custom made pharmaceutical ingredients depending on our professional experts in the pharmaceutical and chemistry industry.

Recently, Kono Chem has been working hard on the research and development of new cardiovascular and anesthesia drugs, we have got good achievements; moreover, we also offer natural anticancer drugs and other pharmaceutical intermediates. As a GMP standardized manufacturer, our products can meet or even exceed the standards of CP2010, USP32, BP2005 and EP4. Presently, 80% and above of our products have been well-recognized in dozens of countries and regions, such as USA, EU, South America and Southeast Asia. There are experienced technicians working for our institutes now, all of them are skilled. Pioneer is looking forward to cooperating with friends all over the world for getting collaborative development; we are willing to work with you to develop new drugs and expand new business, let's work together for bright future.

Process Capability : Suoer critical CO2 extraction method Fermentation expert Other synthesis service

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Details

Chloroprotoferrihem CAS no 16009-13-5

MF: C34H32ClFeN4O4

MW: 651.94

CAS: 16009-13-5

Assay: 99%
Appearance: dark purple crystalline powder

folding edit this paragraph Dark brown flaky crystal, insoluble in water and acetic acid, slightly soluble in 70% ~ 80% ethanol, soluble in dilute sodium hydroxide solution, in sodium hydroxide solution to generate hydroxyl high iron red element, organic alkali soluble in strong (such as trimethylamine and dimethyl aniline) and acetic acid, soluble in concentrated sulfuric acid and lose iron, soluble in dilute ammonia; Transmitted light brown, reflected light for steel blue, until 300 ℃ melting

ITEM	SPECIFICATION	RESULT
Appearance:	fine Powder	Conformed
Odor:	Characteristic	Conformed
Taste:	Characteristic	Conformed
Drying Method:	Spary drying	Conformed
Loss on Drying:	8.0% Max.	4.35%
Bulk Density:	40~60g/100ml.	49.5g/100ml
Total Heavy Metals:	10ppm Max.	Conformed
Arsenic:	2ppm Max.	Conformed
Lead:	2ppm Max.	Conformed
Total plate count:	1,000cfu/g Max.	Conformed
Yeast&mold:	100cfu/g Max.	Conformed
E.Coli:	Negative	Negative
Salmonella:	Negative	Negative
Staphylococcus:	Negative	Negative
Conclusion: The product conforms to the standard.

Factory Supply Top Quality 16009-13-5 with Reasonable Price

Molecular Formula:C34H32ClFeN4O4
Molecular Weight:651.952
Appearance/Colour:Dark purple crystalline powder
Melting Point:300 °C
PSA：109.18000
LogP:4.29920

Hemin(Cas 16009-13-5) Usage

General Description	Heme is a small molecule present either free or bound to hemoglobin in the bloodstream of mammals. This is an alternative source of iron within the host that contains a porphyrin ring containing a Fe2+ ion called hemin.
Biochem/physiol Actions	Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.
Purification Methods	Hemin is purified by recrystallisation from AcOH. Also, hemin (5g) is shaken in pyridine (25mL) till it dissolves, then CHCl3 (40mL) is added, the container is stoppered and shaken for 5minutes (releasing the stopper occasionally). The solution is filtered under slight suction, and the flask and filter are washed with a little CHCl3 (15mL). During this period, AcOH (300mL) is heated to boiling, and saturated aqueous NaCl (5mL) and conc HCl (4mL) are added. The CHCl3 filtrate is poured in a steady stream, with stirring, into the hot AcOH mixture and set aside for 12hours. The crystals are filtered off, washed with 50% aqueous AcOH (50mL), H2O (100mL), EtOH (25mL), Et2O and dried in air. [Fischer Org Synth Coll Vol III 442 1955, Beilstein 26 III/IV 3048.]

InChI:InChI=1/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;/rC34H32ClFeN4O4/c1-7-21-17(3)26-14-31-22(8-2)19(5)29-13-25-18(4)23(9-11-33(41)42)28(38-25)16-32-24(10-12-34(43)44)20(6)30(15-27(21)37-26)40(32)36(35)39(29)31/h7-8,13-16H,1-2,9-12H2,3-6H3,(H,41,42)(H,43,44)/b25-13-,26-14-,27-15-,28-16-,29-13-,30-15-,31-14-,32-16-

16009-13-5 Relevant articles

Impact of metal ions in porphyrin-based applied materials for visible-light photocatalysis: Key information from ultrafast electronic spectroscopy

Kar, Prasenjit,Sardar, Samim,Alarousu, Erkki,Sun, Jingya,Seddigi, Zaki S.,Ahmed, Saleh A.,Danish, Ekram Y.,Mohammed, Omar F.,Pal, Samir Kumar

, p. 10475 - 10483 (2014/08/18)

ProtoporphyrinIX-zinc oxide (PP-ZnO) nan...

Haem-Biosynthese aus L-Glutaminsaeure

Franck, Burchard,Bruse, Manfred,Dahmer, Juergen

, p. 1000 - 1001 (2007/10/02)

16009-13-5 Process route

: iron(III) chloride

: 553-12-8
protoporphyrin IX

: 13496-05-4,16009-13-5
iron(III) protoporphyrin IX chloride

Conditions

Conditions	Yield
In water; dimethyl sulfoxide; for 12h;

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 16009-13-5
(SP-5-13)-chloro(7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato^(4-)-N₂₁,N₂₂,N₂₃,N₂₄)-ferrate^(2-), dihydrogen