Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns, due to its significant healing capacity. Asiaticoside is the main constituent of C. asiatica, which has been used historically in the Ayurvedic system to treat a variety of health issues. Asiaticoside has been observed to increase hydroxyproline content, improve tensile strength, promote epithelialization, stimulate glycosaminoglycan synthesis, and boost antioxidant levels. In regards to collagen, Asiaticoside can promote its synthesis and the remodelling of the collagen matrix.

Asiaticoside, a biochemical modulator, which has antioxidant, anti-inflammatory, antipyretic, anxiolytic-like, anti-gastric ulcers, hepatoprotective, and antidepressant-like effects, it also exhibits significant wound healing activity in normal as well as delayed healing models. Asiaticoside suppressed collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts. It and its derivatives can be regarded as reasonable candidates for a therapeutic Alzheimer's disease drug that protects neurons from Abeta toxicity.

Asiaticoside is a natural triterpenoid found in the herbs of Centella asiatica (L.) Urban. Asiaticoside shows an anxiolytic-like and antidepressant-like effects. The active ingredient asiaticoside of Asiaticoside may be useful for the anti-gastric ulcers. Asiaticoside can also be used in cosmetics material.

• Product name

  Asiaticoside, Triterpene glycoside

• Description

  Triterpene glycoside. Stimulates collagen biosynthesis and glycosaminoglycan synthesis.

• Biological description

  Triterpene glycoside. Stimulates collagen biosynthesis and glycosaminoglycan synthesis. Displays wound-healing activity. Antiaging and anti-infective agent. Active in vivo and in vitro.

• Purity

  > 90%

• CAS Number

  16830-15-2

• Chemical structure